Optimization of truss structures by a stochastic method

This paper presents an original stochastic method of optimization (PGSL) for optimum design of truss structures.PGSL (Probabilistic Global Search Lausanne, developed at the Swiss Federal Institute Leggings of Technology at Lausanne) has been inter-faced with a finite element code, then applied and tested on several size optimization problems of pla

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Differential Response of Coral Assemblages to Thermal Stress Underscores the Complexity in Predicting Bleaching Susceptibility.

Coral bleaching events have been predicted to occur more frequently in the coming decades Fitness Supplies with global warming.The susceptibility of corals to bleaching during thermal stress episodes is dependent on many factors and an understanding of these underlying drivers is crucial for conservation management.In 2013, a mild bleaching episode

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Neoantigen architectures define immunogenicity and drive immune evasion of tumors with heterogenous neoantigen expression

Background Intratumoral heterogeneity (ITH) and subclonal antigen expression blunt antitumor immunity and are associated with poor responses to immune-checkpoint blockade immunotherapy (ICB) in patients with cancer.The underlying mechanisms however thus far remained elusive, preventing the design of novel treatment approaches for patients with high

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